Quick Reference

Comparison of Constipation Treatments

Download

Understanding MiraLax ® And Other OTC Constipation Treatments

+Open List
Type/GENERIC NAME

Osmotic:Polyethylene glycol 3350

HOW IT WORKs:
  • Relieves occasional constipation by attracting water in the colon to ease, hydrate and soften stool to increase the frequency of bowel movements
  • Provides both stool softening and laxative effects 1-9
  • Generally produces a bowel movement in 1-3 days. Many get relief in 1 day
Indication:

Occasional Constipation

CONSIDERATIONS:
  • Will not cause harsh side effects such as gas, bloating, cramping and sudden urgency.
  • Proven safe in patients including elderly 3
  • No known clinically relevant drug-drug interactions 4
  • One of only 2 laxative active ingredients with a Grade A recommendation from the American College of Gastroenterology 10*
  • Do not use if you have kidney disease except under the advice and supervision of a doctor
Type/GENERIC NAME

Stimulant: Bisacodyl Sennosides

HOW IT WORKs:
  • Bisacodyl stimulates the walls of the intestine, causing the muscles to contract and clear the bowel
  • Generally produces a bowel movement in 6-12 hours
Indication:

Occasional Constipation

CONSIDERATIONS:
  • Stimulant laxatives can cause cramps and sudden, urgent bowel movements
  • Do not use Bisacodyl within 1 hour after taking an antacid or milk
  • Sennosides may affect how other drugs work. Should be taken 2 hours before or after other drugs
Type/GENERIC NAME

Bulk-Forming (Fiber): Psyllium Husk

HOW IT WORKS:
  • Softens and increases the bulk of digested food, making it easier for waste to travel through and leave the body
  • Generally produces effect in 12-72 hours
Indication:

Occasional Constipation

CONSIDERATIONS:
  • Can ferment in the intestine, which may cause gas and bloating
  • May affect how well other medicines work. Take at least 2 hours before or 2 hours after prescribed medication
Type/GENERIC NAME

Stool Softener: Docusate Sodium

HOW IT WORKs:
  • Allows water and fats to get into the stool. This helps soften fecal material and makes defecation easier
  • Generally produces effect in 12-72 hours
Indication:

Occasional Constipation

CONSIDERATIONS:
  • Does not force bowel movement
Type/GENERIC NAME

Saline: Magnesium Hydroxide

HOW IT WORKs:
  • Draws water into the intestine leading to a bowel movement
  • Relieves a range of symptoms, including occasional constipation, heartburn, indigestion, and upset stomach
  • Usually produces bowel movement in 1/2 to 6 hours
Indication:

Occasional Constipation

CONSIDERATIONS:
  • Offers cramp-free, gentle relief without harsh stimulants.
  • The only overnight relief liquid with an ingredient that’s easy on your digestive system
  • Patients with kidney disease, a magnesium restricted diet or taking prescription drugs need to consult their doctor before use

www.MiraLAX.com© Bayer

The trademarks depicted in this table are owned by their respective owners.
References: 1. DiPalma JA, et al. A randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipation. Am J Gastroenterol. 2007; 102:1436-1441 2. Stoltz R, et al. An efficacy and consumer preference study of polyethylene glycol 3350 for the treatment of constipation in regular laxative users. Home Health Care Consultant. 2001; 8:21-26. 3. Cleveland MvB, et al. New polyethylene glycol laxative for treatment of constipation in adults: a randomized, double-blind, placebo-controlled study. South Med J. 2001;94:478-481. 4. Data on file, Bayer Healthcare. 5. DiPalma JA, etal. An open-label study of chronic polyethylene glycol laxative use in chronic constipation. Aliment Pharmacol Ther. 2006; 25:703-708. 6. DiPalma JA, et al. A randomized, multicenter comparison of polyethylene glycol laxative and tegaserod in treatment of patients with chronic constipation. Am J Gastroenterol. 2007;102:1964-1971. 7. DiPalma JA, et al. A randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycol laxative. Am J Gastroenterol. 2000;95: 446-450. 8. DiPalma JA, et al. Braintree polyethylene glycol (PEG) laxative for ambulatory and long-term care facility constipation patients: report of randomized, cross-overtrials. Online J Dig Health. 1999;1:1-7. 9. Tran LC, et al. Lack of lasting effectiveness of PEG 3350 laxative treatment of constipation. J Clin Gastroenterol. 2005;39:600-602. 10. American College of Gastroenterology. An evidence-based approach to the management of chronic constipation in NorthAmerica. Am J Gastroenterol. 2005;100(S1):S1-S22. 11. Hsieh C. Treatment of constipation in older adults. Am Fam Physician. 2005;75:2277-2285.

bottle
The #1 GI recommended laxative [2] Use as directed for occasional constipation.